Cherokee caprine3/20/2023 Predictability of different versions of the Caprini score for symptomatic venous thromboembolism (VTE) detected during inpatient treatment by the receiver operating characteristic (ROC) curves. All models including specific COVID-19 scores showed equally high predictability, and use of the original Caprini score is appropriate for patients with COVID-19.ĬOVID-19 Caprini score Prophylaxis Risk assessment Venous thromboembolism.Ĭopyright © 2021 Society for Vascular Surgery. The study identified a significant correlation between the Caprini score and the risk of VTE in patients with COVID-19. Extended antithrombotic treatment was prescribed to 49 (29%) patients with a cumulative incidence of bleeding of 1.8% at 6 months. This did not affect the predictability of the Caprini score. Only symptomatic VTE was reported after discharge with a cumulative incidence of 7.1%. The highest predictability was observed for the original scale when assessed at discharge (death). The Caprini score of all eight versions demonstrated a significant association with inpatient VTE frequency. Clinically relevant nonmajor bleeding was detected in two (1.2%) cases. Of the 168 individuals, 28 (16.7%) admitted to the intensive care unit, 8 (4.8%) required invasive mechanical ventilation, and 8 (4.8%) died. Despite this, symptomatic VTE was detected in 11 (6.5%) inpatients. Patients received prophylactic (enoxaparin 40 mg once daily: 2.4%), intermediate (enoxaparin 80 mg once daily: 76.8%), or therapeutic (enoxaparin 1 mg/kg twice daily: 20.8%) anticoagulation. The maximal score was observed with modification including specific COVID-19 points of 5 to 20 (10.0 ± 3.0). The original Caprini score varied between 2 and 12 (5.4 ± 1.8) at the admission and between 2 and 15 (5.9 ± 2.5) at discharge or death. The association of eight different versions of the Caprini score with VTE events was evaluated.Ī total of 168 patients (83 males and 85 females at the age of 58.3 ± 12.7 years) were admitted to the hospital between April 30 and May 29, 2020, and were discharged or died to the time of data analysis. The secondary end points included those observed during hospitalization (admission to the intensive care unit, a requirement for invasive mechanical ventilation, death, bleeding), and those assessed at 6-month follow-up (symptomatic VTE, bleeding, death). The primary end point was symptomatic venous thromboembolism (VTE) detected during inpatient treatment and confirmed by appropriate imaging testing or autopsy. Besides the original Caprini score (a version of 2005), the modified version added the elevation of D-dimer and specific scores for COVID-19 as follows: two points for asymptomatic, three points for symptomatic, and five points for symptomatic infection with positive D-dimer. The final assessment considered additional risk factors that occurred during inpatient treatment. The score was calculated twice: by the physician on admission and by the investigator at discharge (death). The relevant data were extracted from the electronic medical records with an implemented Caprini score and were retrospectively evaluated. The study aimed to validate the original Caprini score and its modifications considering coronavirus disease (COVID-19) as a severe prothrombotic condition in patients admitted to the hospital.
0 Comments
Leave a Reply.AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |